Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200206 | 0.96 | — | — | |
| Iodide SCHEMBL29042352 | 0.93 | — | — | |
| SCHEMBL811660 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL127053 | 0.93 | — | — | |
| SCHEMBL767933 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL6637499 | 0.93 | — | — | |
| SCHEMBL2351930 | 0.93 | — | — | |
| SCHEMBL10748747 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL30594918 | 0.93 | — | — | |
| SCHEMBL7912373 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317944-A | Acyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118234707-A | Cyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117105811-A | Membrane Fusion Compounds for Delivery of Bioactive Molecules | 日东电工株式会社 | 2023-11-24 | — | — | CN | disclosed |
| CN-113943228-B | Alkaloid pulmonin B derivative, synthesis thereof and application thereof in preventing and treating plant virus and germ diseases | 天津师范大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-111386105-B | Membrane Fusion Compounds for Delivery of Bioactive Molecules | 日东电工株式会社 | 2023-09-15 | — | — | CN | disclosed |
| US-20230192613-A1 | Charged Ion Channel Blockers and Methods for Use | NOCION THERAPEUTICS INC (US) | 2023-06-22 | — | — | US | disclosed |
| US-11603355-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2023-03-14 | — | — | US | disclosed |
| CN-115768351-A | Fluid characterization method | 新生代吉恩公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115066207-A | Method and system for menses group analysis | 新生代吉恩公司 | 2022-09-16 | — | — | CN | disclosed |
| EP-3938345-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| US-10968179-B2 | Charged ion channel blockers and methods for use | Nocion Therapeutics, Inc. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210061763-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2021-03-04 | — | — | US | disclosed |
| CN-107082747-B | Compounds for targeted drug delivery and enhancing siRNA activity | 日东电工株式会社 | 2020-11-20 | — | — | CN | disclosed |
| US-20200290953-A1 | Charged Ion Channel Blockers and Methods for Use | Nocion Therapeutics, Inc. | 2020-09-17 | — | — | US | disclosed |
| WO-2020185830-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. (US) | 2020-09-17 | — | — | WO | disclosed |
| CN-111386105-A | Membrane fusion compounds for delivery of bioactive molecules | 日东电工株式会社 | 2020-07-07 | — | — | CN | disclosed |
| CN-107043334-B | Compounds for targeted drug delivery and enhancing siRNA activity | 日东电工株式会社 | 2020-06-16 | — | — | CN | disclosed |