Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817188 | 0.90 | CYP2C19 (0.41) | CYP2C19TGM2MAPK1AKT1SRC | |
| SCHEMBL12227590 | 0.72 | — | — | |
| SCHEMBL10748377 | 0.71 | SSTR4 (0.41) | CYP2C19 | |
| SCHEMBL23633101 | 0.70 | — | — | |
| SCHEMBL13121494 | 0.70 | — | — | |
| SCHEMBL179807 | 0.69 | — | — | |
| SCHEMBL5742241 | 0.67 | TSHR (0.34) | TSHR | |
| SCHEMBL5319769 | 0.67 | LMNA (0.35) | KDM4ETSHR | |
| SCHEMBL11850898 | 0.65 | BRD4 (0.46) | RAB9ASMN1; SMN2TSHR | |
| SCHEMBL1963300 | 0.65 | BRD4 (0.50) | NPC1RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46357-E1 | Photochromic film, photochromic lens comprising the same, and method of manufacturing photochromic lens | HOYA CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| US-7999989-B2 | Photochromic film, photochromic lens comprising the same, and method of manufacturing photochromic lens | HOYA CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090316246-A1 | PHOTOCHROMIC FILM, PHOTOCHROMIC LENS COMPRISING THE SAME, AND METHOD OF MANUFACTURING PHOTOCHROMIC LENS | HOYA CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |