Propene

Propene

SCHEMBL22409486

C=CC.C=CC(=O)OOC(N)=O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.39
ALDH1A1 P00352 6/20 0.39
FGFR4 P22455 1/20 0.39
HPGD P15428 1/20 0.34
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4769757 0.93
Ethylene SCHEMBL22409415 0.90 TSHR (0.43) TSHRALDH1A1FGFR4HPGDTP53
SCHEMBL419299 0.79 TSHR (0.46) TSHRALDH1A1FGFR4HPGDTP53
SCHEMBL28009874 0.76 TSHR (0.43) TSHRALDH1A1FGFR4HPGDTP53
SCHEMBL3698218 0.72
SCHEMBL11294848 0.70
SCHEMBL10789477 0.70
Acrylic Acid Methyl Ester SCHEMBL28311727 0.70 HCAR2 (0.46) TSHRALDH1A1FGFR4HPGDTP53
Ethane SCHEMBL11593672 0.70 ALDH1A1 (0.43) TSHRALDH1A1FGFR4HPGDTP53
Acrylamide SCHEMBL1147922 0.70 ALDH1A1 (0.79) TSHRALDH1A1FGFR4TP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504448-B2 High-impact, transparent prosthesis material having a low residual MMA content KULZER GMBH (DE) 2022-11-22 US disclosed
US-20200289705-A1 HIGH-IMPACT, TRANSPARENT PROSTHESIS MATERIAL HAVING A LOW RESIDUAL MMA CONTENT KULZER GMBH (DE) 2020-09-17 US disclosed