Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caffeine SCHEMBL5069486 | 0.81 | ADORA2B (0.54) | ALDH1A1LMNATSHRPMP22SLC7A5 | |
| Caffeine SCHEMBL5069479 | 0.81 | ADORA2B (0.54) | ALDH1A1LMNATSHRPMP22SLC7A5 | |
| Tyrosine SCHEMBL28270669 | 0.71 | SLC7A5 (0.92) | ALDH1A1CYP3A4SLC7A5ALPIPKM | |
| Tyrosine SCHEMBL5222909 | 0.71 | SLC7A5 (0.92) | ALDH1A1CYP3A4SLC7A5ALPIPKM | |
| Tyrosine SCHEMBL6374042 | 0.71 | SLC7A5 (0.92) | ALDH1A1CYP3A4SLC7A5ALPIPKM | |
| Tyrosine SCHEMBL28297995 | 0.71 | SLC7A5 (0.92) | ALDH1A1CYP3A4SLC7A5ALPIPKM | |
| Tyrosine SCHEMBL11520027 | 0.71 | SLC7A5 (1.00) | ALDH1A1LMNACYP3A4MAPTPMP22 | |
| Tyrosine SCHEMBL20787 | 0.71 | SLC7A5 (1.00) | ALDH1A1LMNACYP3A4MAPTPMP22 | |
| Tyrosine SCHEMBL1581 | 0.71 | SLC7A5 (1.00) | ALDH1A1LMNACYP3A4MAPTPMP22 | |
| Tyrosine SCHEMBL638520 | 0.71 | SLC7A5 (1.00) | ALDH1A1LMNACYP3A4MAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938528-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING DEPRESSION | Duke University (US) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020185580-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING DEPRESSION | DUKE UNIVERSITY (US) | 2020-09-17 | — | — | WO | disclosed |