SCHEMBL22415

SCHEMBL22415

OCC1CCC(F)(F)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16577416 1.00
SCHEMBL18027852 1.00
SCHEMBL19032264 0.86 APLNR (0.58)
SCHEMBL22907 0.84 APLNR (0.55)
SCHEMBL12206360 0.81 APLNR (0.46)
SCHEMBL29224607 0.81 APLNR (0.46)
SCHEMBL364651 0.78
SCHEMBL20548690 0.77
SCHEMBL8040596 0.76 APLNR (0.41)
SCHEMBL1986520 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117895064-A Phosphate polymer quasi-solid electrolyte, in-situ solid immobilization preparation method and application 深圳大学 2024-04-16 CN claimed
EP-4288426-B1 QUINOXALINE DERIVATIVES AND USES THEREOF BLACK DIAMOND THERAPEUTICS INC (US) 2026-02-04 EP disclosed
US-12528815-B2 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer NXERA PHARMA UK LIMITED (GB) 2026-01-20 US disclosed
WO-2025226892-A1 SPIROCYCLE-CONTAINING DIAMINOMETHYLENE PYRIMIDINE-2,4,6-TRIONE AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2025-10-30 WO disclosed
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP disclosed
US-20250282762-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2025-09-11 US disclosed
US-12281101-B2 Bicyclic lactams and methods of use thereof GENENTECH, INC. (US) 2025-04-22 US disclosed
US-12252482-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2025-03-18 US disclosed
US-20250002479-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2025-01-02 US disclosed
US-12172984-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2024-12-24 US disclosed
US-20100094000-A1 PYRAZOLE COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-04-15 US disclosed
US-20100094000-A1 PYRAZOLE COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-04-15 US disclosed
US-20090325942-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2009-12-31 US disclosed
US-20090325942-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2009-12-31 US disclosed
US-20090325942-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2009-12-31 US disclosed
EP-2114937-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS Sanofi-Aventis (FR) 2009-11-11 EP disclosed
US-20090048203-A1 SUBSTITUTED ADENINES AND THE USES THEREOF ASTRAZENECA AB (SE) 2009-02-19 US disclosed
WO-2008089892-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2008-07-31 WO disclosed
WO-2008089892-A1 PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS SANOFI-AVENTIS (FR) 2008-07-31 WO disclosed
CN-101072787-A Substituted adenines and the use thereof ASTRAZENECA AB (SE) 2007-11-14 CN disclosed