Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22416019 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM5CHRM1PEPD | |
| SCHEMBL22415869 | 0.77 | CHRM5 (0.42) | CHRM5PEPDMEN1KMT2AALDH1A1 | |
| SCHEMBL22415855 | 0.77 | CHRM5 (0.42) | CHRM5PEPDMEN1KMT2AALDH1A1 | |
| SCHEMBL19576544 | 0.77 | CHRM5 (0.42) | CHRM5PEPDMEN1KMT2AALDH1A1 | |
| SCHEMBL19576793 | 0.76 | CHRM5 (0.45) | CHRM5PEPDMEN1KMT2AALDH1A1 | |
| SCHEMBL19576637 | 0.76 | CHRM5 (0.45) | CHRM5PEPDMEN1KMT2AALDH1A1 | |
| SCHEMBL6033629 | 0.73 | KEAP1 (0.36) | — | |
| SCHEMBL13761134 | 0.73 | PEPD (0.42) | PEPDMEN1BLMKMT2A | |
| SCHEMBL7907529 | 0.73 | PEPD (0.42) | PEPDMEN1BLMKMT2A | |
| SCHEMBL9376361 | 0.73 | PEPD (0.42) | PEPDMEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452485-B1 | ARGINASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | ONCOARENDI THERAPEUTICS SA (PL) | 2020-09-09 | — | — | EP | disclosed |