Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 11/20 | 0.50 |
| ▸ | KDR | P35968 | 11/20 | 0.50 |
| ▸ | LCK | P06239 | 10/20 | 0.50 |
| ▸ | MET | P08581 | 3/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 7/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ABL2 | P42684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418477 | 0.84 | TEK (0.52) | FLT3TEKKDRLCKMET | |
| SCHEMBL22418414 | 0.83 | BTK (0.55) | TEKLCKSRCRIPK2 | |
| SCHEMBL22418461 | 0.79 | FLT3 (0.62) | FLT3LCKMETAXLSRC | |
| SCHEMBL22676745 | 0.78 | SRC (0.67) | TEKKDRLCKSRCRIPK2 | |
| SCHEMBL29407781 | 0.78 | SRC (0.55) | FLT3TEKKDRLCKMET | |
| SCHEMBL22677981 | 0.78 | SRC (0.55) | FLT3TEKKDRLCKMET | |
| SCHEMBL23917434 | 0.75 | SRC (0.61) | FLT3TEKKDRLCKMET | |
| SCHEMBL18044717 | 0.75 | KDR (0.59) | FLT3TEKKDRLCKMET | |
| SCHEMBL7005521 | 0.75 | LCK (0.72) | FLT3TEKKDRLCKAXL | |
| SCHEMBL30582619 | 0.75 | SRC (0.57) | TEKKDRLCKSRCRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182188-A1 | SUBSTITUTED HETEROARYL COMPOUND, COMPOSITION OF SAME, AND USES THEREOF | 习峰 | 2020-09-17 | — | — | WO | disclosed |