Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 9/20 | 0.52 |
| ▸ | LCK | P06239 | 9/20 | 0.52 |
| ▸ | KDR | P35968 | 9/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 7/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ABL2 | P42684 | 2/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.47 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418463 | 0.84 | FLT3 (0.52) | TEKLCKKDRMETAXL | |
| SCHEMBL28772346 | 0.84 | EIF2AK3 (0.44) | METAXLSRCFLT3EGFR | |
| SCHEMBL22676745 | 0.83 | SRC (0.67) | TEKLCKKDRSRCABL1 | |
| SCHEMBL28633632 | 0.82 | EIF2AK3 (0.51) | KDRSRCFLT3ABL1EGFR | |
| SCHEMBL22677981 | 0.81 | SRC (0.55) | TEKLCKKDRMETAXL | |
| SCHEMBL29407781 | 0.81 | SRC (0.55) | TEKLCKKDRMETAXL | |
| SCHEMBL23917434 | 0.80 | SRC (0.61) | TEKLCKKDRMETAXL | |
| SCHEMBL30442066 | 0.80 | FLT3 (0.51) | LCKMETAXLFLT3EIF2AK3 | |
| SCHEMBL18044717 | 0.80 | KDR (0.59) | TEKLCKKDRMETAXL | |
| SCHEMBL7005521 | 0.80 | LCK (0.72) | TEKLCKKDRAXLSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689991-B | Substituted heteroaryl compounds, compositions and uses thereof | 习峰 | 2023-06-09 | — | — | CN | disclosed |
| CN-111689991-A | Substituted heteroaryl compounds, compositions and uses thereof | 习峰 | 2020-09-22 | — | — | CN | disclosed |
| WO-2020182188-A1 | SUBSTITUTED HETEROARYL COMPOUND, COMPOSITION OF SAME, AND USES THEREOF | 习峰 | 2020-09-17 | — | — | WO | disclosed |