Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.42 |
| ▸ | CDC25B | P30305 | 7/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 3/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22419917 | 1.00 | HTR1A (0.42) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL30063068 | 0.86 | HTR1A (0.43) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL16588038 | 0.84 | SSTR1 (0.53) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL20033560 | 0.84 | SSTR1 (0.53) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL24256784 | 0.84 | SSTR1 (0.53) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL23705049 | 0.84 | SSTR1 (0.53) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL22419918 | 0.84 | HTR1A (0.42) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL22419916 | 0.84 | HTR1A (0.42) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL30277436 | 0.84 | HTR1A (0.43) | HTR1APTPN1CDC25BSSTR1SSTR2 | |
| SCHEMBL30063888 | 0.84 | HTR1A (0.43) | HTR1APTPN1CDC25BSSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10772946-B2 | Immunogenic compositions against S. aureus | SANOFI PASTEUR (FR) | 2020-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10772946-B2 | Immunogenic compositions against S. aureus | CD4, CSGALNACT1, B3GNT2 | HTR1A 4605/4885PTPN1 668/4885CDC25B 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.