SCHEMBL2242017

SCHEMBL2242017

CC(C)C(=O)Oc1ccc(I)cc1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.66
LMNA P02545 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA2 P00918 2/20 0.39
RAB9A P51151 1/20 0.39
ALOX15 P16050 1/20 0.39
HTR1D P28221 1/20 0.38
HTR1B P28222 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TPMT P51580 1/20 0.37
APP P05067 1/20 0.37
GSK3B P49841 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21795326 0.89 ELANE (0.79) ELANELMNAMEN1KMT2ACA2
SCHEMBL4754215 0.84 ELANE (0.47) ELANELMNACA2RAB9AATM
SCHEMBL21325759 0.83 ELANE (0.70) ELANELMNACA2RAB9AALOX15
SCHEMBL5186261 0.81 ELANE (0.68) ELANELMNAMEN1KMT2ACA2
SCHEMBL12616903 0.81 ELANE (0.68) ELANELMNAMEN1KMT2ACA2
SCHEMBL891415 0.81 ELANE (0.68) ELANELMNAMEN1KMT2A
SCHEMBL177167 0.80 LMNA (0.64) ELANELMNAMEN1KMT2ARAB9A
SCHEMBL19925263 0.80 ELANE (0.61) ELANELMNACA2RAB9AALOX15
SCHEMBL4904945 0.79 ELANE (0.66) ELANELMNAMEN1KMT2ACA2
SCHEMBL4683823 0.79 ELANE (0.66) ELANELMNAKMT2ACA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673523-B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-18 US disclosed
US-20110207040-A1 IMAGE HOLDING MEMBER FOR IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-08-25 US disclosed
US-20090231240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE FUJI XEROX CO., LTD. (JP) 2009-09-17 US disclosed