Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5973685 | 0.98 | CYP3A4 (0.58) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL27543233 | 0.98 | CYP3A4 (0.58) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL27518040 | 0.98 | CYP3A4 (0.58) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL392484 | 0.85 | TDP1 (0.61) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL29353815 | 0.82 | CYP3A4 (0.69) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL78293 | 0.82 | CYP3A4 (0.69) | CYP3A4TSHRGAATHRBTDP1 | |
| Methane SCHEMBL28785435 | 0.80 | CYP3A4 (0.67) | CYP3A4TSHRGAATHRBTDP1 | |
| Hydrochloric Acid SCHEMBL970605 | 0.80 | CYP3A4 (0.67) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL11822059 | 0.80 | TSHR (0.52) | CYP3A4TSHRGAATHRBTDP1 | |
| SCHEMBL31435677 | 0.80 | CYP3A4 (0.67) | CYP3A4TSHRGAATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754606-A | Phenoxazinediamine derivatives and/or phenothiazine diamine derivatives and preparation method thereof | 南京工业大学 | 2021-12-07 | — | — | CN | claimed |
| WO-2022213975-A1 | COMPOUNDS TARGETING Y220C MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-10-13 | — | — | WO | disclosed |
| CN-114656418-A | (E) -benzo five-membered ring-styryl sulfonium salt derivatives, and preparation and application thereof | 同济大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-111138380-B | Method for continuously synthesizing benzothiadiazole compound | 浙江工业大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-113754606-A | Phenoxazinediamine derivatives and/or phenothiazine diamine derivatives and preparation method thereof | 南京工业大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-111138380-A | Method for continuously synthesizing benzothiadiazole compound | 浙江工业大学 | 2020-05-12 | — | — | CN | disclosed |
| EP-3251694-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit (Oxford) Limited (GB) | 2017-12-06 | — | — | EP | disclosed |
| US-20170155053-A1 | Molecular and Polymeric Semiconductors and Related Devices | USINVEST LLC | 2017-06-01 | — | — | US | disclosed |
| WO-2016025632-A1 | MOLECULAR AND POLYMERIC SEMICONDUCTORS AND RELATED DEVICES | POLYERA CORPORATION (US) | 2016-02-18 | — | — | WO | disclosed |
| EP-1986633-B1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORP PLC (GB) | 2014-07-30 | — | — | EP | disclosed |
| EP-0116827-B1 | PROCESS FOR THE PREPARATION OF BENZOTHIAZOLES | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4978476-A | Side chain polymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1990-12-18 | — | — | US | disclosed |
| US-4808723-A | Process for the preparation of benzothiazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0061082-B1 | PROCESS FOR THE PREPARATION OF 2,3-DIHYDRO-4H-1,4-BENZOTHIAZINES | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0116827-A2 | Process for the preparation of benzothiazoles | BAYER AG (DE) | 1984-08-29 | — | — | EP | disclosed |
| US-4393206-A | DEHYDROCYCLIZATION OF 2-(2-HYDROXYALKYL)-THIOANILINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0061082-A1 | Process for the preparation of 2,3-dihydro-4H-1,4-benzothiazines | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |
| US-3985885-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |