SCHEMBL78293

SCHEMBL78293

Nc1ccc([N+](=O)[O-])cc1N

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.69
TSHR P16473 3/20 0.69
GAA P10253 2/20 0.69
THRB P10828 1/20 0.69
TDP1 Q9NUW8 9/20 0.68
ALDH1A1 P00352 6/20 0.65
ALOX15 P16050 2/20 0.62
HTT P42858 1/20 0.59
MEN1 O00255 3/20 0.55
MAPT P10636 3/20 0.55
KMT2A Q03164 3/20 0.55
GFER P55789 2/20 0.55
LMNA P02545 1/20 0.54
HSD17B10 Q99714 1/20 0.52
POLB P06746 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ATM Q13315 1/20 0.51
APEX1 P27695 1/20 0.51
CASP6 P55212 1/20 0.51
CTDSP1 Q9GZU7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353815 1.00 CYP3A4 (0.69) CYP3A4TSHRGAATHRBTDP1
Methane SCHEMBL28785435 0.98 CYP3A4 (0.67) CYP3A4TSHRGAATHRBTDP1
Hydrochloric Acid SCHEMBL970606 0.98 CYP3A4 (0.67) CYP3A4TSHRGAATHRBTDP1
SCHEMBL31435677 0.98 CYP3A4 (0.67) CYP3A4TSHRGAATHRBTDP1
Hydrochloric Acid SCHEMBL970605 0.98 CYP3A4 (0.67) CYP3A4TSHRGAATHRBTDP1
Sulfuric Acid SCHEMBL969448 0.89 GAA (0.63) CYP3A4TSHRGAATHRBTDP1
Sulfuric Acid SCHEMBL30000516 0.89 GAA (0.63) CYP3A4TSHRGAATHRBTDP1
2-Amino-4-Nitrophenol SCHEMBL10386089 0.88 GAA (0.92) CYP3A4TSHRGAATHRBTDP1
SCHEMBL10487196 0.86 CYP3A4 (0.64) CYP3A4TSHRGAATHRBTDP1
SCHEMBL5489713 0.84 TDP1 (0.79) CYP3A4TSHRGAATHRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5931 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528793-B2 Compounds for treating tuberculosis NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2026-01-20 US claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
CN-114106341-B Comb copolymer, preparation method and application thereof 广州立邦涂料有限公司 2025-05-02 CN claimed
CN-115980205-B Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product 江苏省食品药品监督检验研究院 2025-04-22 CN claimed
CN-119661511-A Benzimidazole compound and application thereof 山东农业大学 2025-03-21 CN claimed
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
CN-119064244-A Method for rapidly and accurately measuring somatic cell number 中国计量科学研究院 2024-12-03 CN claimed
CN-115911342-B Silicon anode material and preparation method thereof, anode and lithium ion battery 江苏中兴派能电池有限公司 2024-11-22 CN claimed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP claimed
EP-4408376-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT Kao Corporation (JP) 2024-08-07 EP claimed
US-4870049-A TRANSFER SHEET FOR THERMAL PRINTING SHARP KABUSHIKI KAISHA (JP) 1989-09-26 US claimed
US-4844712-A Dyeing composition for fibrous materials COMBE INCORPORATED (US) 1989-07-04 US claimed
EP-0279016-A2 Powdered hair dye HOYU CO., LTD. (JP) 1988-08-24 EP claimed
US-4764174-A Nitrophenylenediamine dye composition having improved deposition on human hair and wool HELENE CURTIS, INC. (US) 1988-08-16 US claimed
EP-0271713-A2 Method for preparing aqueous solutions containing chromogenic materials SAVYON DIAGNOSTICS LTD. (IL) 1988-06-22 EP claimed
EP-0009641-B1 POLYPHOSPHAZENE POLYMERS CONTAINING ORTHO-DIFUNCTIONAL PHENYLENE SUBSTITUENTS AND METHOD FOR PREPARING SAME THE FIRESTONE TIRE & RUBBER COMPANY (US) 1983-03-23 EP claimed
EP-0040641-A1 PROCESS FOR ISOLATING AND PURIFYING A FRACTION CAPABLE OF INHIBITING MUTAGENICITY OF A MUTAGENIC MATERIAL FROM BURDOCK JUICE KANEBO, LTD. (JP) 1981-12-02 EP claimed
EP-0001246-B1 PREPARATION OF 2-(3'- OR 4'-AMINOPHENYL)-5(OR 6)-AMINOBENZIMIDAZOLES CASSELLA Aktiengesellschaft (DE) 1981-02-25 EP claimed
US-4221898-A Polyphosphazene polymers containing ortho-difunctional phenylene substitutents THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-09-09 US claimed
EP-0009641-A1 Polyphosphazene polymers containing ortho-difunctional phenylene substituents and method for preparing same THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-04-16 EP claimed