Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PRLHR | P49683 | 4/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22424260 | 0.94 | P2RX7 (0.36) | P2RX7MAPK14HPGDPRLHR | |
| SCHEMBL22424125 | 0.92 | P2RX7 (0.36) | P2RX7MAPK14PRLHRABL1 | |
| SCHEMBL25051697 | 0.92 | P2RX7 (0.36) | P2RX7MAPK14PRLHRABL1 | |
| SCHEMBL22424300 | 0.92 | P2RX7 (0.36) | P2RX7PRLHR | |
| SCHEMBL22423986 | 0.89 | MAPK14 (0.34) | P2RX7MAPK14HPGD | |
| SCHEMBL22423978 | 0.88 | MAPK14 (0.34) | P2RX7MAPK14HPGD | |
| SCHEMBL22424624 | 0.88 | P2RX7 (0.34) | P2RX7MAPK14PRLHR | |
| SCHEMBL22424133 | 0.87 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL22424129 | 0.87 | P2RX7 (0.34) | P2RX7PRLHR | |
| SCHEMBL22424131 | 0.87 | MAPK1 (0.34) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |