Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CLPP | Q16740 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22424573 | 0.90 | PRLHR (0.51) | PRLHRLMNAALDH1A1GAAKMT2A | |
| SCHEMBL22424568 | 0.89 | PRLHR (0.51) | PRLHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL22424571 | 0.89 | PRLHR (0.51) | PRLHRLMNAALDH1A1GAAKMT2A | |
| SCHEMBL22424695 | 0.89 | PRLHR (0.53) | PRLHRLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL22424554 | 0.89 | PRLHR (0.50) | PRLHRLMNAKMT2AMAPTHPGD | |
| SCHEMBL22424283 | 0.89 | PRLHR (0.50) | PRLHRLMNASMN1; SMN2CLPPKMT2A | |
| SCHEMBL22423999 | 0.88 | PRLHR (0.50) | PRLHRLMNAALDH1A1GAAHTT | |
| SCHEMBL22424229 | 0.88 | PRLHR (0.52) | PRLHRHDAC6GRM5 | |
| SCHEMBL22424687 | 0.87 | PRLHR (0.49) | PRLHRLMNAKMT2AMAPTTP53 | |
| SCHEMBL22424139 | 0.87 | PRLHR (0.49) | PRLHRLMNAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |