Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRLHR | P49683 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22424573 | 0.93 | PRLHR (0.51) | PRLHRHDAC6GRM5HTR1APDE5A | |
| SCHEMBL22423999 | 0.92 | PRLHR (0.50) | PRLHRMAPTLMNAALDH1A1KDM4E | |
| SCHEMBL22424695 | 0.91 | PRLHR (0.53) | PRLHRHDAC6GRM5HTR1APDE5A | |
| SCHEMBL22424014 | 0.89 | PRLHR (0.51) | PRLHRHDAC6GRM5MAPTLMNA | |
| SCHEMBL22424568 | 0.89 | PRLHR (0.51) | PRLHRHDAC6GRM5HTR1APDE5A | |
| SCHEMBL22424554 | 0.89 | PRLHR (0.50) | PRLHRHDAC6GRM5HTR1APDE5A | |
| SCHEMBL22424229 | 0.88 | PRLHR (0.52) | PRLHRHDAC6GRM5HTR1A | |
| SCHEMBL22424555 | 0.86 | PRLHR (0.51) | PRLHRHDAC6GRM5HTR1APDE5A | |
| SCHEMBL22424283 | 0.85 | PRLHR (0.50) | PRLHRHDAC6GRM5HTR1APDE5A | |
| SCHEMBL22424345 | 0.85 | PRLHR (0.47) | PRLHRHDAC6GRM5PDE5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |