Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | PRKACG | P22612 | 1/20 | 0.52 |
| ▸ | PRKACB | P22694 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22425356 | 1.00 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CMEN1 | |
| SCHEMBL30370083 | 0.83 | HTR2C (0.45) | PRKACAPRKACGPRKACBHTR2CMEN1 | |
| SCHEMBL27758952 | 0.83 | PRKACA (0.41) | PRKACAPRKACGPRKACBMAP4K1CTSK | |
| SCHEMBL7353494 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CMEN1 | |
| SCHEMBL432870 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CMAP4K1 | |
| SCHEMBL14839631 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CCTSK | |
| SCHEMBL21723230 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CMEN1 | |
| SCHEMBL30824548 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CMAP4K1 | |
| SCHEMBL28785154 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBHTR2CMAP4K1 | |
| SCHEMBL28028671 | 0.81 | PRKACA (0.59) | PRKACAPRKACGPRKACBMAP4K1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162191-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2022-05-26 | — | — | US | disclosed |
| WO-2020182666-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2020-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162191-A1 | SMALL MOLECULE MODULATORS OF IL-17 | IL17A, IL15, IL2 | PRKACA 282/4885PRKACG 283/4885PRKACB 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.