Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | PRKACG | P22612 | 1/20 | 0.59 |
| ▸ | PRKACB | P22694 | 1/20 | 0.59 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22425354 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBMAP4K1CTSK | |
| SCHEMBL7353494 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBCSNK1DCSNK1E | |
| SCHEMBL21723230 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBCSNK1DCSNK1E | |
| SCHEMBL28785154 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBMAP4K1CTSK | |
| SCHEMBL14839631 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBCTSKHTR2B | |
| SCHEMBL432870 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBMAP4K1CTSK | |
| SCHEMBL22425356 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBMAP4K1CTSK | |
| SCHEMBL30824548 | 0.81 | PRKACA (0.52) | PRKACAPRKACGPRKACBMAP4K1CTSK | |
| SCHEMBL3399522 | 0.80 | PRKACA (0.47) | PRKACAPRKACGPRKACBMAP4K1DDB1 | |
| Hydrochloric Acid SCHEMBL25320856 | 0.79 | PRKACA (0.51) | PRKACAPRKACGPRKACBMAP4K1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854108-A | Pyrrolotriazinone derivatives as pi3k inhibitors | ALMIRALL SA | 2015-08-19 | — | — | CN | disclosed |