Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22412170 | 0.87 | GAA (0.54) | GAAALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL29684152 | 0.87 | GAA (0.54) | GAAALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL22425988 | 0.80 | GAA (0.41) | GAAALDH1A1KDM4ESMN1; SMN2CA2 | |
| SCHEMBL31172068 | 0.80 | GAA (0.41) | GAAALDH1A1KDM4ESMN1; SMN2CA2 | |
| SCHEMBL22412145 | 0.80 | GAA (0.41) | GAAALDH1A1KDM4ESMN1; SMN2CA2 | |
| SCHEMBL28676506 | 0.78 | GAA (0.47) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28676505 | 0.78 | GAA (0.47) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3720231 | 0.77 | GAA (0.56) | GAAALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4528153 | 0.76 | GAA (0.67) | GAAALDH1A1MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL5913154 | 0.75 | GAA (0.65) | GAAALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185755-A1 | TYK2 INHIBITORS AND USES THEREOF | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2020-09-17 | — | — | WO | disclosed |