SCHEMBL224293

SCHEMBL224293

Cc1cc(C2(C)CCCCC2)c(O)c(C2(C)CCCCC2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.66
TSHR P16473 1/20 0.66
ALOX12 P18054 1/20 0.66
NPSR1 Q6W5P4 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
ATM Q13315 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TP53 P04637 1/20 0.50
GAA P10253 1/20 0.50
ACHE P22303 2/20 0.42
RARB P10826 3/20 0.38
RARG P13631 3/20 0.38
RARA P10276 2/20 0.36
SELL P14151 1/20 0.36
SELP P16109 1/20 0.36
SELE P16581 1/20 0.36
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
PDE7A Q13946 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373474 0.90 GLA (0.60) GLATSHRALOX12NPSR1MEN1
SCHEMBL39469 0.90 GLA (0.60) GLATSHRALOX12NPSR1MEN1
SCHEMBL14571979 0.87 TSHR (0.57) GLATSHRALOX12NPSR1MEN1
SCHEMBL39101 0.86 GLA (0.73) GLATSHRALOX12NPSR1MEN1
SCHEMBL31176239 0.86 GLA (0.73) GLATSHRALOX12NPSR1MEN1
SCHEMBL9744265 0.86 ALOX12 (0.56) GLATSHRALOX12NPSR1MEN1
SCHEMBL29464977 0.86 GLA (0.73) GLATSHRALOX12NPSR1MEN1
SCHEMBL11813522 0.84 GLA (0.55) GLATSHRALOX12NPSR1MEN1
SCHEMBL10899051 0.84 GLA (0.55) GLATSHRALOX12NPSR1MEN1
SCHEMBL6400015 0.84 GLA (0.55) GLATSHRALOX12NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012579-B1 PRESSURE-SENSITIVE MARK-RECORDING SYSTEMS AND SOLUTIONS FOR USE IN SUCH SYSTEMS MONSANTO EUROPE S.A./N.V. (BE) 1983-06-22 EP claimed
EP-0012579-A2 Pressure-sensitive mark-recording systems and solutions for use in such systems MONSANTO EUROPE S.A./N.V. (BE) 1980-06-25 EP claimed
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
EP-0535221-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 EP disclosed
EP-0535217-A1 LUBRICATING COMPOSITIONS. LUBRIZOL CORP (US) 1993-04-07 EP disclosed
WO-1992018588-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
WO-1992018589-A1 LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1992-10-29 WO disclosed
EP-0471071-A1 HIGH TEMPERATURE FUNCTIONAL FLUIDS. LUBRIZOL CORP (US) 1992-02-19 EP disclosed
WO-1991013133-A2 HIGH TEMPERATURE FUNCTIONAL FLUIDS THE LUBRIZOL CORPORATION (US) 1991-09-05 WO disclosed
EP-0012579-B1 PRESSURE-SENSITIVE MARK-RECORDING SYSTEMS AND SOLUTIONS FOR USE IN SUCH SYSTEMS MONSANTO EUROPE S.A./N.V. (BE) 1983-06-22 EP disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed
US-3984940-A Degradable plastic REICH MURRAY 1976-10-12 US disclosed