⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498181 | 0.80 | — | — | |
| SCHEMBL9348 | 0.71 | — | — | |
| SCHEMBL7628295 | 0.67 | — | — | |
| SCHEMBL478038 | 0.59 | — | — | |
| SCHEMBL4132146 | 0.58 | — | — | |
| SCHEMBL1585661 | 0.50 | — | — | |
| SCHEMBL2326 | 0.45 | — | — | |
| SCHEMBL34570 | 0.45 | — | — | |
| SCHEMBL25407819 | 0.41 | — | — | |
| SCHEMBL17688348 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 19842 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131776-A1 | BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION | 上海邈基生物科技有限公司 | 2024-06-27 | — | — | WO | claimed |
| CN-117157299-B | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118084864-A | PRMT4 inhibitor, and pharmaceutical composition, pharmaceutical preparation and application thereof | 北京福元医药股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117946297-A | Modified diallyl phthalate resin, preparation method thereof and curing composition | 常州强力电子新材料股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-113272301-B | Heterocyclic compound, intermediate, preparation method and application thereof | 武汉朗来科技发展有限公司 | 2024-04-26 | — | — | CN | claimed |
| EP-4349815-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2024-04-10 | — | — | EP | claimed |
| CN-113087718-B | Thienopyrimidinone compounds and medical application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| US-20240034729-A9 | HETEROCYCLIC COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2024-02-01 | — | — | US | claimed |
| CN-117466906-A | Oridonin derivative, preparation method thereof, pharmaceutical composition and application | 中国人民解放军海军军医大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117157299-A | Tricyclic heterocyclic derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| US-4407824-A | ANTIINFLAMMATORY, ANALYGESIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-10-04 | — | — | US | claimed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | claimed |
| US-4352760-A | Organic compounds substituted heptadeca-5,9- and 5,10-dienoic acid | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | claimed |
| US-4287338-A | Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts | THE UPJOHN COMPANY (US) | 1981-09-01 | — | — | US | claimed |
| EP-0024282-A1 | Benzoyl derivatives, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1981-03-04 | — | — | EP | claimed |
| US-4200628-A | ANTIBIOTICS, BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1980-04-29 | — | — | US | claimed |
| US-4176119-A | OXADIAZOLOPYRIMIDINE DERIVATIVES USEFUL AS VASODILATORS OR HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | claimed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |
| US-4150131-A | Substituted oxadiazolopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1979-04-17 | — | — | US | claimed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | claimed |