⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277583 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL23295202 | 0.66 | — | — | |
| SCHEMBL20598 | 0.66 | — | — | |
| SCHEMBL7628295 | 0.59 | — | — | |
| SCHEMBL2243 | 0.59 | — | — | |
| SCHEMBL1585661 | 0.54 | — | — | |
| SCHEMBL77749 | 0.50 | — | — | |
| SCHEMBL2326 | 0.47 | — | — | |
| SCHEMBL34570 | 0.47 | — | — | |
| SCHEMBL17688343 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032864-A1 | Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S LABORATORIES LIMITED | 2005-02-10 | — | — | US | claimed |
| US-12030858-B2 | PARP inhibitors for treating cancer and asthma | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-4370505-A1 | HERBICIDAL PHENYLURACILS | BASF SE (DE) | 2024-05-22 | — | — | EP | disclosed |
| EP-3843726-B1 | PARP INHIBITORS FOR TREATING CANCER AND ASTHMA | UNIV OREGON HEALTH & SCIENCE (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20230345941-A1 | HERBICIDAL PHENYLETHERS | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230175005-A1 | PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES | BASF SE (DE) | 2023-06-08 | — | — | US | disclosed |
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-20230157289-A1 | HERBICIDAL PHENYLURACILS | BASF SE (DE) | 2023-05-25 | — | — | US | disclosed |
| CN-116113634-A | Modulus modifier and film thereof | 齐默尔根公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | Tonix Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20020123502-A1 | Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION & REDDY-CHEMINOR, INC. | 2002-09-05 | — | — | US | disclosed |
| US-6372750-B2 | COMPOUNDS SUCH AS 5-(4-(2-(2,4-DIMETHYL-6-OXO-1,6-DIHYDRO-1-PYRIMIDINYL)ETHOXY)PHENYL METHYL)THIZOLIDINE-2,4-DIONE MADE BY CYCLIZATION, CHEMICAL REDUCTION, HYDROLYSIS, AZOLIDINEDIONE DERIVATIVES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-04-16 | — | — | US | disclosed |
| US-6310069-B1 | INTERMEDIATES TO AZOLIDINEDIONE ANTIDIABETIC COMPOUNDS SUCH AS 5-(4-(2-(2,4-DIMETHYL-6-OXO-1,6-DIHYDRO-1-PYRIMIDINYL)ETHOXY)PHENYL METHYL)THIAZOLIDINE-2,4-DIONES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-10-30 | — | — | US | disclosed |
| US-20010031759-A1 | Novel heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION & REDDY- CHEMINOR, INC. | 2001-10-18 | — | — | US | disclosed |
| US-6114526-A | REACTING AN AMINO DERIVATIVE WITH A HETEROCYCLIC DIONE COMPOUND TO FORM AN ANTIDIABETIC AGENT | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-09-05 | — | — | US | disclosed |
| US-5985884-A | TREATMENT AND/OR PROPHYLAXIS OF DISEASES OR CONDITIONS IN WHICH INSULIN RESISTANCE IS THE UNDERLYING PATHOPHYSIOLOGICAL MECHANISM SUCH AS TYPE II DIABETES, IMPAIRED GLUCOSE TOLERANCE, DYSLIPIDAEMIA, HYPERTENSION, CORONARY HEART DISEASE | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-11-16 | — | — | US | disclosed |
| US-5885997-A | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-23 | — | — | US | disclosed |
| WO-1998049150-A1 | TRIAZINE DERIVATIVES, THEIR PRODUCTION AND AGROCHEMICAL COMPOSITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |
| US-5801173-A | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-09-01 | — | — | US | disclosed |
| WO-1998006709-A1 | CYCLIC UREA COMPOUNDS, THEIR PRODUCTION AND USE AS HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-19 | — | — | WO | disclosed |