Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923501 | 0.81 | TSHR (0.50) | TSHRALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL9976123 | 0.79 | TSHR (0.53) | TSHRALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL20356526 | 0.75 | TSHR (0.44) | TSHRALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL16456042 | 0.75 | TSHR (0.44) | TSHRALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL20356280 | 0.72 | TSHR (0.39) | TSHRALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15580117 | 0.71 | TSHR (0.54) | TSHRADRA2AADRA2BADRA2CNOS3 | |
| SCHEMBL22291907 | 0.70 | TSHR (0.58) | TSHRNOS3NOS2HTR5APLAU | |
| SCHEMBL19140170 | 0.68 | TSHR (0.46) | TSHRALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL14088325 | 0.67 | TSHR (0.54) | TSHRALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL1194687 | 0.67 | TSHR (0.95) | TSHRALDH1A1KDM4EADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020186220-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2020-09-17 | — | — | WO | disclosed |