Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923501 | 0.81 | TSHR (0.50) | TSHRALDH1A1KDM4ENOS3NOS2 | |
| SCHEMBL22995932 | 0.80 | KDM4E (0.63) | TSHRALDH1A1KDM4EPNMTNOS3 | |
| SCHEMBL30952113 | 0.80 | KDM4E (0.63) | TSHRALDH1A1KDM4EPNMTNOS3 | |
| SCHEMBL22431952 | 0.79 | TSHR (0.48) | TSHRALDH1A1KDM4ENOS3NOS2 | |
| SCHEMBL20356526 | 0.75 | TSHR (0.44) | TSHRALDH1A1KDM4ENOS3NOS2 | |
| SCHEMBL16456042 | 0.75 | TSHR (0.44) | TSHRALDH1A1KDM4ENOS3NOS2 | |
| SCHEMBL6703737 | 0.71 | CA1 (0.40) | TSHR | |
| SCHEMBL1194687 | 0.71 | TSHR (0.95) | TSHRALDH1A1KDM4ENOS3NOS2 | |
| SCHEMBL31703623 | 0.71 | TSHR (0.95) | TSHRALDH1A1KDM4ENOS3NOS2 | |
| SCHEMBL8170948 | 0.71 | TSHR (0.54) | TSHRALDH1A1KDM4ENOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9412955-B2 | Fluorescent isoindoline dyes | UNIVERSAL DISPLAY CORPORATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150318494-A1 | Fluorescent Isoindoline Dyes | UNIV SOUTHERN CALIFORNIA (US) | 2015-11-05 | — | — | US | disclosed |
| US-9079885-B2 | Fluorescent isoindoline dyes | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-20120153266-A1 | FLUORESCENT ISOINDOLINE DYES | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150318494-A1 | Fluorescent Isoindoline Dyes | OCIAD1, OCIAD2, OXA1L | TSHR 4746/4885ALDH1A1 1077/4885KDM4E 3497/4885 |
| US-20120153266-A1 | FLUORESCENT ISOINDOLINE DYES | OCIAD1, OCIAD2, OXA1L | TSHR 4746/4885ALDH1A1 1077/4885KDM4E 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.