Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249449 | 0.89 | PLAU (0.53) | F2PLAUPLATPLGELANE | |
| SCHEMBL2245473 | 0.87 | PLAU (0.42) | F2PLAUPLATPLGELANE | |
| SCHEMBL13736066 | 0.82 | PLAU (0.37) | F2PLAUPLATPLGELANE | |
| Trifluoroacetic Acid SCHEMBL13736752 | 0.80 | PLAU (0.37) | F2PLAUPLATPLGELANE | |
| Trifluoroacetic Acid SCHEMBL13736056 | 0.77 | PLAU (0.35) | F2PLAUPLATPLGELANE | |
| Trifluoroacetic Acid SCHEMBL13736165 | 0.75 | PLAU (0.32) | F2PLAUPLAT | |
| Trifluoroacetic Acid SCHEMBL13738338 | 0.75 | PLAU (0.32) | F2PLAUPLAT | |
| SCHEMBL24225368 | 0.71 | ELANE (0.49) | F2PLAUPLATPLGELANE | |
| SCHEMBL11109783 | 0.71 | CTDSP1 (0.49) | CTDSP1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL28138500 | 0.71 | ALDH1A1 (0.60) | CTDSP1LMNASMN1; SMN2CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940856-B1 | NOVEL UROKINASE INHIBITORS | UNIV ANTWERPEN (BE) | 2014-10-08 | — | — | EP | disclosed |
| US-8003627-B2 | Urokinase inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2011-08-23 | — | — | US | disclosed |
| US-20080312191-A1 | Novel Urokinase Inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2008-12-18 | — | — | US | disclosed |
| EP-1940856-A1 | NOVEL UROKINASE INHIBITORS | Universiteit Antwerpen (BE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007045496-A1 | NOVEL UROKINASE INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312191-A1 | Novel Urokinase Inhibitors | PLAU, PLAUR, SERPINE1 | F2 241/4885PLAU 1/4885PLAT 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.