Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26803605 | 0.97 | TSHR (0.33) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL22433238 | 0.89 | ALDH1A1 (0.37) | TSHRHSD17B10ALDH1A1 | |
| SCHEMBL19809986 | 0.84 | USP2 (0.37) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL18235764 | 0.84 | KMT2A (0.38) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL10029365 | 0.84 | KMT2A (0.38) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL19809988 | 0.84 | USP2 (0.37) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL12826647 | 0.84 | TSHR (0.34) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL25908790 | 0.83 | CYP3A4 (0.34) | TSHRCYP3A4HTTRECQLMEN1 | |
| SCHEMBL22433237 | 0.81 | MEN1 (0.36) | TSHRCYP3A4RECQLMEN1HPGD | |
| SCHEMBL12745459 | 0.80 | CYP3A4 (0.33) | TSHRCYP3A4HTTRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185695-A1 | ANALOGUES AND DERIVATIVES OF CEPHALOTAXINE AND METHODS FOR MAKING AND USING THE COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2020-09-17 | — | — | WO | disclosed |