Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 8/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433331 | 1.00 | KLK7 (0.54) | KLK7KLK5CTSLSYKPPARA | |
| SCHEMBL22687090 | 0.88 | CTSL (0.57) | KLK7KLK5CTSLSYKPPARA | |
| SCHEMBL22687091 | 0.88 | CTSL (0.57) | KLK7KLK5CTSLSYKPPARA | |
| SCHEMBL8234039 | 0.85 | CTSL (0.59) | KLK7KLK5CTSLSYKPPARA | |
| SCHEMBL30337362 | 0.83 | ATM (0.51) | ATM | |
| SCHEMBL26045089 | 0.83 | ATM (0.51) | ATM | |
| SCHEMBL30613282 | 0.83 | ATM (0.51) | ATM | |
| SCHEMBL26045030 | 0.83 | ATM (0.51) | ATM | |
| SCHEMBL124116 | 0.80 | PPARG (0.42) | KLK7KLK5CTSLPPARACTSS | |
| SCHEMBL13537921 | 0.80 | KLK7 (0.59) | KLK7KLK5CTSLSYKPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185999-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |