Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KLK7 | P49862 | 2/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433339 | 1.00 | MAPT (0.60) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL14014416 | 0.91 | KLK7 (0.63) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL13120843 | 0.91 | KLK7 (0.63) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL2329143 | 0.90 | KLK7 (0.67) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL25540903 | 0.90 | KLK7 (0.67) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL2329138 | 0.90 | KLK7 (0.67) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL22090527 | 0.88 | SIRT2 (0.51) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL7425992 | 0.87 | SYK (0.58) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL7424195 | 0.87 | SYK (0.58) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL10825402 | 0.87 | LMNA (0.62) | MAPTKLK7KLK5ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185999-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |