Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434019 | 0.92 | GSTP1 (0.44) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL22434463 | 0.88 | GSTP1 (0.40) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL22434379 | 0.86 | MEN1 (0.62) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL29359210 | 0.85 | MAPT (0.63) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL22434375 | 0.85 | MAPT (0.63) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL17970190 | 0.85 | KMT2A (0.66) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL29349733 | 0.82 | MAPT (0.62) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL30366389 | 0.82 | ALB (0.49) | MEN1KMT2AMAPTHTTFTO | |
| SCHEMBL3201232 | 0.82 | ALB (0.49) | MEN1KMT2AMAPTHTTFTO | |
| SCHEMBL15171578 | 0.80 | MEN1 (0.51) | MEN1KMT2AUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185610-A1 | NEW TECHNOLOGY TO CONJUGATE THE TACCALONOLIDE MICROTUBULE STABILIZERS WITH LINKERS/PAYLOADS | DU LIN (US) | 2020-09-17 | — | — | WO | disclosed |