Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366389 | 1.00 | ALB (0.49) | ALBFTOKCNH2MMP14JAK2 | |
| Fluorescein SCHEMBL29996358 | 0.86 | FTO (0.52) | ALBFTOMEN1MAPTHPGD | |
| SCHEMBL14769388 | 0.86 | ALB (0.47) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL17787480 | 0.85 | ALB (0.47) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL6450383 | 0.85 | ALB (0.49) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL3499473 | 0.84 | ALB (0.56) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL917141 | 0.84 | ALB (0.58) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL9215437 | 0.84 | FTO (0.38) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL20353152 | 0.82 | FTO (0.55) | ALBFTOKCNH2MMP14JAK2 | |
| SCHEMBL22434464 | 0.82 | MEN1 (0.54) | ALBFTOKCNH2MMP14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144845-A1 | SUBSTITUTED PYRROLO[1,2-a]QUINOXALIN-4(5H)-ONES AS CX3CR1 ANTAGONISTS | UNIV DREXEL (US) | 2022-05-12 | — | — | US | disclosed |
| US-20200062768-A1 | CX3CR1 Small Molecule Antagonists, and Methods Using Same | DREXEL UNIVERSITY | 2020-02-27 | — | — | US | disclosed |
| US-7667048-B2 | Green and orange fluorescent labels and their uses | ARIES ASSOCIATES, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7592143-B2 | Methods of treating diseases responsive to induction of apoptosis and screening assays | CYTOVIA, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1054062-B1 | GLYCOSYLTRANSFERASE AND DNA ENCODING THE SAME | KYOWA HAKKO BIO CO LTD (JP) | 2009-06-03 | — | — | EP | disclosed |
| US-20080261235-A1 | Novel Green and Orange Fluorescent Labels and Their Uses | BHATT RAM | 2008-10-23 | — | — | US | disclosed |
| EP-1620564-A4 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | CYTOVIA INC (US) | 2008-03-12 | — | — | EP | disclosed |
| US-7317111-B2 | Green and orange fluorescent labels and their uses | ARIES ASSOCIATES, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070112008-A1 | Saframycins, analogues and uses thereof | MYERS ANDREW G | 2007-05-17 | — | — | US | disclosed |
| US-20070112008-A1 | Saframycins, analogues and uses thereof | MYERS ANDREW G | 2007-05-17 | — | — | US | disclosed |
| US-20050004026-A1 | Methods of treating diseases responsive to induction of Apoptosis and screening assays | CYTOVIA, INC. | 2005-01-06 | — | — | US | disclosed |
| US-6830908-B2 | Enzymatic polypetide for use in modifying carbohydrates | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| WO-2004094647-A2 | METHODS OF TREATING DISEASES RESPONSIVE TO INDUCTION OF APOPTOSIS AND SCREENING ASSAYS | CYTOVIA, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| WO-2004089295-A2 | HOMOGENEOUS AND HETEROGENEOUS ASSAY METHODS USING NUCLEATION CENTERS AND NOVEL COVALENT CHEMISTRIES FOR THE RAPID MEASUREMENT OF PHOSPHORYLATION AND DE-PHOSPHORYLATION | CHROMAGEN, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040137532-A1 | Antibody competition test (act) for the qualitative and conformation dependent quantitative detection of the conformation changes of p-glycoprotein and other cell surface receptors, pumps and proteins, and uses thereof | SOFT FLOW HUNGARY KFT. (HU) | 2004-07-15 | — | — | US | disclosed |
| US-20040106806-A1 | Novel green and orange fluorescent labels and their uses | ARIES ASSOCIATES, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004027388-A2 | NOVEL GREEN AND ORANGE FLUORESCENT LABELS AND THEIR USES | CHROMAGEN, INC. (US) | 2004-04-01 | — | — | WO | disclosed |
| EP-1373891-A2 | QUANTITATIVE DETECTION OF THE CONFORMATION CHANGES OF P-GLYCOPROTEIN | SOFT FLOW HUNGARY KFT. (HU) | 2004-01-02 | — | — | EP | disclosed |
| US-6475761-B1 | Glycosyltransferase and DNA encoding the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| WO-2002071061-A2 | QUANTITATIVE DETECTION OF THE CONFORMATION CHANGES OF P-GLYCOPROTEIN | SOFT FLOW HUNGARY KFT. (HU) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004026-A1 | Methods of treating diseases responsive to induction of Apoptosis and screening assays | HEATR6, HEATR1, AIP | ALB 2063/4885FTO 4804/4885KCNH2 4577/4885 |
| US-20070112008-A1 | Saframycins, analogues and uses thereof | MYC, MAN1B1, MRPS18A | ALB 4047/4885FTO 3615/4885KCNH2 3591/4885 |
| US-20220144845-A1 | SUBSTITUTED PYRROLO[1,2-a]QUINOXALIN-4(5H)-ONES AS CX3CR1 ANTAGONISTS | CX3CR1, CCR5, CCL2 | ALB 4086/4885FTO 1942/4885KCNH2 1133/4885 |
| US-20200062768-A1 | CX3CR1 Small Molecule Antagonists, and Methods Using Same | CX3CR1, CCR5, CXCR3 | ALB 4546/4885FTO 3392/4885KCNH2 940/4885 |
| US-20040106806-A1 | Novel green and orange fluorescent labels and their uses | CD69, ANXA5, ANXA6 | ALB 1390/4885FTO 1578/4885KCNH2 3461/4885 |
| US-20080261235-A1 | Novel Green and Orange Fluorescent Labels and Their Uses | CD69, ANXA6, ANXA5 | ALB 1701/4885FTO 1977/4885KCNH2 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.