SCHEMBL224392

SCHEMBL224392

CC(C)c1cccc(OP(=O)(O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.53
INPPL1 O15357 3/20 0.47
INPP5A Q14642 3/20 0.47
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
MDM4 O15151 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
TYR P14679 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CA5A P35218 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19764645 0.88 PTPN5 (0.47) SRCKDM4EALDH1A1SMN1; SMN2HDAC4
SCHEMBL31141513 0.85 NPSR1 (0.46) KDM4EALDH1A1SMN1; SMN2HDAC4HDAC8
SCHEMBL224391 0.85 NPSR1 (0.46) KDM4EALDH1A1SMN1; SMN2HDAC4HDAC8
SCHEMBL9715026 0.85 POLB (0.48) SRCKDM4EALDH1A1SMN1; SMN2HDAC4
Phenyl Dihydrogen Phosphate SCHEMBL28273698 0.84 SRC (0.70) SRCINPPL1INPP5ATDP1LMNA
SCHEMBL30947664 0.81 NPSR1 (0.51) SRCKDM4EALDH1A1SMN1; SMN2HDAC4
SCHEMBL224029 0.81 NPSR1 (0.51) SRCKDM4EALDH1A1SMN1; SMN2HDAC4
SCHEMBL28781315 0.81 NPSR1 (0.51) SRCKDM4EALDH1A1SMN1; SMN2HDAC4
SCHEMBL130697 0.80 INPPL1 (0.71) SRCINPPL1INPP5AKDM4EALDH1A1
Phenyl Dihydrogen Phosphate SCHEMBL29103148 0.80 SRC (0.70) SRCINPPL1INPP5ATDP1PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813840-A Flame-retardant polyvinyl chloride resin and preparation method thereof 宜宾天原科创设计有限公司 2023-09-29 CN claimed
US-20140179811-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS HICKORY SPRINGS MFG CO (US) 2014-06-26 US claimed
US-8575225-B2 Use of low triphenylphosphate, high phosphorous content isopropyl phenyl phosphates as flame retardants in polyurethane or polyisocyanurate foams HICKORY SPRINGS MANUFACTURING COMPANY (US) 2013-11-05 US claimed
US-20100130654-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS ALBEMARIE CORPORATION (US) 2010-05-27 US claimed
US-20100120930-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS ALBEMARLE CORPORATION (US) 2010-05-13 US claimed
CN-101652420-A Use of low triphenyl phosphate, high phosphorous content isopropyl phenyl phosphate as flame retardant in polyurethane or polyisocyanurate foams ALBEMARLE CORP US 2010-02-17 CN claimed
CN-101646726-A Use of low triphenyl phosphate, high phosphorous content isopropyl phenyl phosphate as flame retardant in resins ALBEMARLE CORP US 2010-02-10 CN claimed
EP-2134781-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS Albemarle Corporation (US) 2009-12-23 EP claimed
EP-2134782-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS Albemarle Corporation (US) 2009-12-23 EP claimed
WO-2008118695-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN RESINS ALBEMARLE CORPORATION (US) 2008-10-02 WO claimed
WO-2008118699-A1 USE OF LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES AS FLAME RETARDANTS IN POLYURETHANE OR POLYISOCYANURATE FOAMS ALBEMARLE CORPORATION (US) 2008-10-02 WO claimed
CN-116813840-A Flame-retardant polyvinyl chloride resin and preparation method thereof 宜宾天原科创设计有限公司 2023-09-29 CN disclosed
US-10988500-B2 Lipid A mimics, methods of preparation, and uses thereof IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2021-04-27 US disclosed
US-20200109160-A1 LIPID A MIMICS, METHODS OF PREPARATION, AND USES THEREOF IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2020-04-09 US disclosed
US-20180009833-A1 LIPID A MIMICS, METHODS OF PREPARATION, AND USES THEREOF IMMUNOVACCINE TECHNOLOGIES INC. (CA) 2018-01-11 US disclosed
WO-2008030792-A2 FLAME RETARDED TEXTILE PRODUCTS AND A METHOD OF MAKING THE SAME ALBEMARLE CORPORATION (US) 2008-03-13 WO disclosed
WO-2007127691-A2 LOW TRIPHENYLPHOSPHATE, HIGH PHOSPHOROUS CONTENT ISOPROPYL PHENYL PHOSPHATES WITH HIGH ORTHO ALKYLATION ALBERMARLE CORPORATION (US) 2007-11-08 WO disclosed
EP-0485586-A4 PHOSPHATE ESTER FLAME RETARDANT MIXTURE AND FOAMED RESINS CONTAINING SAME 1992-11-04 EP disclosed
EP-0485586-A1 PHOSPHATE ESTER FLAME RETARDANT MIXTURE AND FOAMED RESINS CONTAINING SAME. ALBRIGHT & WILSON AMERICAS (US) 1992-05-20 EP disclosed
US-4163731-A HYDRAULIC FLUIDS CIBA-GEIGY AG (CH) 1979-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200109160-A1 LIPID A MIMICS, METHODS OF PREPARATION, AND USES THEREOF CD14, LPAR4, TLR4 SRC 1690/4885INPPL1 353/4885INPP5A 267/4885
US-20180009833-A1 LIPID A MIMICS, METHODS OF PREPARATION, AND USES THEREOF CD14, LPAR4, TLR4 SRC 1690/4885INPPL1 353/4885INPP5A 267/4885
US-10988500-B2 Lipid A mimics, methods of preparation, and uses thereof CD14, LPAR4, TLR4 SRC 1690/4885INPPL1 353/4885INPP5A 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.