Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23816546 | 0.71 | CRBN (0.57) | — | |
| SCHEMBL3582878 | 0.68 | TDP1 (0.49) | — | |
| SCHEMBL14466750 | 0.68 | TDP1 (0.49) | — | |
| SCHEMBL24783320 | 0.66 | CRBN (0.54) | — | |
| SCHEMBL24783239 | 0.65 | CYP2A6 (0.36) | — | |
| SCHEMBL22440127 | 0.64 | KDM4E (0.38) | — | |
| SCHEMBL24783470 | 0.64 | CRBN (0.56) | — | |
| SCHEMBL22440083 | 0.63 | CRBN (0.34) | — | |
| SCHEMBL24783277 | 0.63 | CYP1A2 (0.40) | — | |
| SCHEMBL922860 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710002-A2 | DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION | C4 Therapeutics, Inc. (US) | 2020-09-23 | — | — | EP | disclosed |