Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22443440 | 1.00 | SLC6A4 (0.33) | SLC6A4FPR2DPP4DPP8DPP9 | |
| SCHEMBL22443444 | 1.00 | SLC6A4 (0.33) | SLC6A4FPR2DPP4DPP8DPP9 | |
| SCHEMBL22443443 | 1.00 | SLC6A4 (0.33) | SLC6A4FPR2DPP4DPP8DPP9 | |
| SCHEMBL22443612 | 0.83 | SLC6A3 (0.39) | — | |
| SCHEMBL22443659 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL22443660 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL22443565 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL22443561 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL22443567 | 0.82 | HTR2A (0.40) | — | |
| SCHEMBL11116777 | 0.82 | SLC6A2 (0.38) | SLC6A4FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941468-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | Atrogi AB (SE) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020188301-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2020-09-24 | — | — | WO | disclosed |