Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22443618 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAAELANEACHEKMT2A | |
| SCHEMBL22443617 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAAELANEACHEKMT2A | |
| SCHEMBL22443666 | 0.91 | GAA (0.41) | ALDH1A1GAAELANEACHELMNA | |
| SCHEMBL22443677 | 0.91 | GAA (0.41) | ALDH1A1GAAELANEACHELMNA | |
| SCHEMBL22443667 | 0.91 | GAA (0.41) | ALDH1A1GAAELANEACHELMNA | |
| SCHEMBL22453840 | 0.77 | VEGFA (0.43) | ACHESIGMAR1 | |
| SCHEMBL22443386 | 0.76 | SPHK2 (0.41) | ALDH1A1ACHESIGMAR1 | |
| Ammonia Solution, Strong SCHEMBL29243782 | 0.76 | CCR3 (0.41) | — | |
| SCHEMBL22443385 | 0.76 | SPHK2 (0.41) | ALDH1A1ACHESIGMAR1 | |
| SCHEMBL22443391 | 0.73 | ALDH1A1 (0.40) | ALDH1A1ACHEKMT2AMEN1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941468-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | Atrogi AB (SE) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020188301-A1 | HETEROCYCLYL(PHENYL)METHANOL COMPOUNDS USEFUL IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2020-09-24 | — | — | WO | disclosed |