SCHEMBL22444490

SCHEMBL22444490

CN(C)c1ccc2cc3cc(-c4nc5ccccc5s4)c(=O)oc3cc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.61
▸ PIK3CB P42338 1/20 0.61
▸ APP P05067 2/20 0.57
▸ ALK Q9UM73 2/20 0.52
▸ KDM4E B2RXH2 5/20 0.42
▸ ALDH1A1 P00352 5/20 0.42
▸ POLB P06746 3/20 0.42
▸ KEAP1 Q14145 1/20 0.42
▸ MAPT P10636 9/20 0.40
▸ TP53 P04637 3/20 0.40
▸ MEN1 O00255 6/20 0.40
▸ KMT2A Q03164 6/20 0.40
▸ NPC1 O15118 5/20 0.40
▸ RAB9A P51151 4/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ L3MBTL1 Q9Y468 3/20 0.40
▸ GAA P10253 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ HTT P42858 3/20 0.39
▸ ATM Q13315 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874253 1.00 PIK3CD (0.61) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL31022177 0.91 PIK3CD (0.69) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL2381840 0.91 PIK3CD (0.69) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL29696056 0.89 PIK3CD (0.58) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL1133687 0.89 PIK3CD (0.58) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL30674288 0.86 PIK3CD (0.71) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL20593861 0.83 PIK3CD (0.61) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL13322414 0.81 PIK3CD (0.64) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL6325083 0.81 PIK3CD (0.60) PIK3CDPIK3CBAPPALKKDM4E
SCHEMBL9351976 0.80 PIK3CD (0.52) PIK3CDPIK3CBAPPALKKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220163545-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2022-05-26 — — US disclosed
EP-3943919-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE National University Corporation Gunma University (JP) 2022-01-26 — — EP disclosed
CN-113597547-A Fluorescent imaging agent for lipid droplets in cells and tissues 国立大学法人群马大学 2021-11-02 — — CN disclosed
WO-2020189721-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE 国立大学法人群馬大学 2020-09-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220163545-A1 REAGENT FOR FLUORESCENCE IMAGING OF LIPID DROPLETS IN CELL AND TISSUE PLIN3, STARD7, PLIN5 PIK3CD 2720/4885PIK3CB 2779/4885APP 3469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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