PLIN5 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL20846	1.00	2/20
SCHEMBL22146	1.00	2/20
Menadione (SCHEMBL25970)	1.00	2/20
SCHEMBL28181	1.00	2/20
SCHEMBL478244	1.00	2/20
SCHEMBL5111	0.95	2/20
SCHEMBL9619	0.95	2/20
SCHEMBL19685	0.95	2/20
SCHEMBL97495	0.95	2/20
SCHEMBL97496	0.95	2/20
SCHEMBL155137	0.95	2/20
SCHEMBL187662	0.95	2/20
SCHEMBL509571	0.95	2/20
SCHEMBL546046	0.95	2/20
SCHEMBL546073	0.95	2/20
Water (SCHEMBL424880)	0.86	2/20
Chloroform (SCHEMBL84057)	0.79	2/20
SCHEMBL184544	0.75	2/20
Cinnamic Acid (SCHEMBL1332)	0.73	2/20
Cinnamic Acid (SCHEMBL1333)	0.73	2/20

Clinical trials — most relevant to PLIN5 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Mechanisms Underlying Metabolic Syndrome in Obesity	PHASE4	COMPLETED
Effect Of Exenatide Treatment on Liver Fat Content in Patients With Diabetes	PHASE4	COMPLETED
Mechanisms of Lipodystrophy in HIV-Infected Pateints	PHASE4	COMPLETED
Acute Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon	PHASE4	COMPLETED
Cholic Acid for Hepatic Steatosis in Lipodystrophy	PHASE2	COMPLETED
Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects	PHASE2	COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins	EARLY_PHASE1	RECRUITING
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.	nan	UNKNOWN
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Association of Genes to Resistance to Weight Loss in Obese Patients	nan	COMPLETED
Familial Partial Lipodystrophy Study	nan	COMPLETED
MARS: Magnetic Resonance Study: A Novel Assessment of Placental Function	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Efficacy of Sodium Glucose Cotransporter 2 Inhibitors on Non-Alcoholic Fatty Liver Disease	nan	NOT_YET_RECRUITING
The Role of Ectopic Fat and Heart Attack Risk in HIV	nan	RECRUITING
Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea	nan	COMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Triglyceride-rich LIPoproteins and INflammatory Cytokines After Oral FAT Loading as Potential Early Biomarkers of the Risk of Progression Towards DIABETES and Development of Complications. LIPINFAT Diabetes Study.	nan	RECRUITING
Role of Dairy Products in Weight Maintenance	nan	COMPLETED
Gene Expression in Obesity and Insulin Resistance	nan	COMPLETED
Dietary Protein and Hepatic Fat Accumulation	nan	COMPLETED
In and ex Vivo Mitochondrial Function of the Heart	nan	COMPLETED
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome	nan	UNKNOWN
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With Classic Polycystic Ovary Syndrome (PCOS)	nan	NOT_YET_RECRUITING
The Investigation of the Mechanism of Cachexia Occurrence for Patients With Gastrointestinal Cancer	nan	UNKNOWN
BATokines as Biomarkers of Brown Fat in Humans	nan	ACTIVE_NOT_RECRUITING
Hepatic Glycogen and Fat Oxidation	nan	COMPLETED
Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a PLIN5 binder may also engage these)

Protein	Name	Similarity
A6QLL0	—	1.000	A6QLL0 →
Q8BVZ1	—	1.000	Q8BVZ1 →
M0R7Z9	—	1.000	M0R7Z9 →
B0FJL7	—	1.000	B0FJL7 →
PLIN1	Perilipin-1	0.992	landscape →
PLIN3	Perilipin-3	0.982	landscape →
Q8CGN5	—	0.981	Q8CGN5 →
Q9DBG5	—	0.980	Q9DBG5 →
Q5BLZ2	—	0.979	Q5BLZ2 →
P43884	—	0.978	P43884 →
P0DKW5	—	0.978	P0DKW5 →
P0DTR8	—	0.977	P0DTR8 →
Q9GJU3	—	0.977	Q9GJU3 →
Q9GLM6	—	0.976	Q9GLM6 →
A0A0D9S1R0	—	0.976	A0A0D9S1R0 →
P0DUI5	—	0.976	P0DUI5 →
P0DKW6	—	0.975	P0DKW6 →
P10517	—	0.975	P10517 →
P0DUI8	—	0.975	P0DUI8 →
Q5RAV8	—	0.975	Q5RAV8 →
P0DUI9	—	0.975	P0DUI9 →
P0DUZ0	—	0.974	P0DUZ0 →
P05770	—	0.974	P05770 →
P0DN39	—	0.974	P0DN39 →
Q86XR2	—	0.974	Q86XR2 →
P0DTS3	—	0.973	P0DTS3 →
P0DKW7	—	0.973	P0DKW7 →
P0DOC3	—	0.973	P0DOC3 →
P0DN41	—	0.973	P0DN41 →
G5CBM7	—	0.972	G5CBM7 →