Dalapon

Dalapon

SCHEMBL22444532

CC(Cl)(Cl)C(=O)O.O=C(Nc1ccc(Cl)c(Cl)c1)C1CC1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
HTT P42858 2/20 0.59
LMNA P02545 1/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
ALOX12 P18054 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
EPHX2 P34913 2/20 0.55
MGLL Q99685 1/20 0.50
CYP3A4 P08684 1/20 0.50
GLA P06280 1/20 0.49
NAMPT P43490 1/20 0.49
EPHX1 P07099 1/20 0.49
MAOB P27338 1/20 0.48
USP2 O75604 1/20 0.47
MALT1 Q9UDY8 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dalapon SCHEMBL9674076 1.00 KMT2A (0.60) KMT2AMEN1HTTLMNAHPGD
SCHEMBL9706943 0.88 KMT2A (0.73) KMT2AMEN1HTTLMNAHPGD
SCHEMBL134242 0.88 KMT2A (0.73) KMT2AMEN1HTTLMNAHPGD
SCHEMBL29462402 0.88 KMT2A (0.73) KMT2AMEN1HTTLMNAHPGD
SCHEMBL2239611 0.81 HPGD (0.64) KMT2AMEN1HTTLMNAHPGD
SCHEMBL10114377 0.80 KMT2A (0.59) KMT2AMEN1HTTLMNAHPGD
SCHEMBL10133755 0.80 KMT2A (0.59) KMT2AMEN1HTTLMNAHPGD
SCHEMBL7522405 0.80 MEN1 (0.61) KMT2AMEN1HTTLMNAHPGD
SCHEMBL12563633 0.79 KMT2A (0.72) KMT2AMEN1HTTLMNAHPGD
Hydrochloric Acid SCHEMBL1942210 0.78 MEN1 (0.60) KMT2AMEN1HTTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020189576-A1 CRYSTAL OF HETEROCYCLIC AMIDE COMPOUND AND METHOD FOR PRODUCING SAME 日産化学株式会社 2020-09-24 WO disclosed