Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134242 | 0.92 | KMT2A (0.73) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9706943 | 0.92 | KMT2A (0.73) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29462402 | 0.92 | KMT2A (0.73) | HPGDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2241850 | 0.86 | ALDH1A1 (0.60) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4096062 | 0.86 | PTPN1 (0.58) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7522405 | 0.86 | MEN1 (0.61) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2492827 | 0.85 | HPGD (0.56) | HPGDALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1942210 | 0.84 | MEN1 (0.60) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL26279821 | 0.84 | HPGD (0.61) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8278410 | 0.84 | ALDH1A1 (0.60) | HPGDALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295088-A1 | INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES MELLITUS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2023-09-21 | — | — | US | disclosed |
| US-20230295088-A1 | INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES MELLITUS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2023-09-21 | — | — | US | disclosed |
| US-20110195979-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295088-A1 | INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES MELLITUS | IAPP, GPR119, INSR | HPGD 1451/4885ALDH1A1 3323/4885TSHR 609/4885 |
| US-20110195979-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | NAT1, NHERF1, ADORA1 | HPGD 1896/4885ALDH1A1 507/4885TSHR 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.