SCHEMBL22444533

SCHEMBL22444533

CCOCCCCc1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.60
ADRA2A P08913 2/20 0.60
ADORA3 P0DMS8 2/20 0.60
TACR2 P21452 2/20 0.60
SLC6A2 P23975 2/20 0.60
SLC6A4 P31645 2/20 0.60
SLC6A3 Q01959 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
SHBG P04278 1/20 0.60
TP53 P04637 1/20 0.60
CYP3A4 P08684 1/20 0.60
HSPD1 P10809 1/20 0.60
ADRB3 P13945 1/20 0.60
HTR2C P28335 1/20 0.60
HSPE1 P61604 1/20 0.60
HIF1A Q16665 1/20 0.60
TST Q16762 1/20 0.60
HSD17B10 Q99714 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22444757 0.98 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL10752499 0.94 ESR1 (0.57) ESR1ADRA2AADORA3TACR2SLC6A2
4-Nonylphenol SCHEMBL28835277 0.93 PTGS2 (0.73) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL28633769 0.88 ESR1 (0.57) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL25230817 0.87 ESR1 (0.69) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL28656684 0.87 ESR1 (0.63) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9260139 0.87 CYP3A4 (0.75) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL4578977 0.86 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL10750273 0.86 ESR1 (0.54) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL9260721 0.85 ESR1 (0.61) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-113574041-A Method for producing bisphenol and method for producing polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed