Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26896455 | 0.88 | MME (0.51) | KDM4ENPC1RAB9AMMEACE | |
| SCHEMBL5869511 | 0.85 | KDM4E (0.47) | KDM4ENPC1RAB9AMMEACE | |
| SCHEMBL5870373 | 0.85 | KDM4E (0.47) | KDM4ENPC1RAB9AMMEACE | |
| SCHEMBL31688647 | 0.83 | PPARA (0.53) | MMEACECPA1ACE2GPR132 | |
| SCHEMBL20905557 | 0.83 | ACE (0.56) | KDM4ENPC1RAB9AMMEACE | |
| SCHEMBL17542524 | 0.81 | TAAR1 (0.54) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL29855228 | 0.81 | TAAR1 (0.54) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL16203413 | 0.81 | TAAR1 (0.54) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL22444630 | 0.81 | KDM4E (0.52) | KDM4ENPC1RAB9ABCHE | |
| SCHEMBL10188901 | 0.81 | KDM4E (0.52) | KDM4ENPC1RAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |