Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.56 |
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22444667 | 0.91 | MDM2 (0.53) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL29633915 | 0.89 | MDM2 (0.46) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL28741484 | 0.89 | MDM2 (0.46) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL22444618 | 0.87 | MDM4 (0.52) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL22444871 | 0.86 | MDM2 (0.56) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL25259836 | 0.86 | MDM2 (0.53) | MDM2MDM4TP53CASP3SLC17A5 | |
| SCHEMBL25259834 | 0.86 | MDM2 (0.53) | MDM2MDM4TP53CASP3SLC17A5 | |
| SCHEMBL22444788 | 0.85 | MDM2 (0.63) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL22444972 | 0.85 | MDM2 (0.63) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL22444598 | 0.85 | MDM2 (0.56) | MDM2MDM4TP53TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |