Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22447490 | 0.87 | MCL1 (0.60) | MCL1LMNADDR1RAB9AMMP13 | |
| SCHEMBL22447483 | 0.85 | MCL1 (0.54) | MCL1LMNADDR1PIK3CARAB9A | |
| SCHEMBL31723379 | 0.80 | MCL1 (0.56) | MCL1LMNADDR1RAB9AHDAC6 | |
| SCHEMBL30987319 | 0.79 | MCL1 (0.58) | MCL1LMNADDR1RAB9AHTT | |
| SCHEMBL12933340 | 0.79 | MCL1 (0.57) | MCL1LMNADDR1RAB9AHTT | |
| SCHEMBL22447583 | 0.78 | MCL1 (0.57) | MCL1LMNADDR1PIK3CARAB9A | |
| SCHEMBL4210572 | 0.77 | MCL1 (0.61) | MCL1LMNADDR1RAB9AHTT | |
| SCHEMBL13820349 | 0.77 | MCL1 (0.56) | MCL1LMNADDR1RAB9ATNF | |
| SCHEMBL22447510 | 0.76 | MCL1 (0.60) | MCL1LMNADDR1RAB9AMMP13 | |
| SCHEMBL22447414 | 0.76 | MCL1 (0.64) | MCL1LMNAPIK3CARAB9AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712143-A1 | QUINAZOLINONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |