Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933340 | 0.87 | MCL1 (0.57) | MCL1LMNADDR1MAPK1POLB | |
| SCHEMBL30987319 | 0.84 | MCL1 (0.58) | MCL1LMNADDR1MAPK1POLB | |
| SCHEMBL13820349 | 0.82 | MCL1 (0.56) | MCL1LMNADDR1MAPK1POLB | |
| SCHEMBL30987352 | 0.81 | PDE5A (0.43) | MCL1LMNADDR1TNFHDAC6 | |
| SCHEMBL22447490 | 0.81 | MCL1 (0.60) | MCL1LMNADDR1POLBTNF | |
| SCHEMBL22447583 | 0.80 | MCL1 (0.57) | MCL1LMNADDR1MAPK1TNF | |
| SCHEMBL22447486 | 0.80 | MCL1 (0.56) | MCL1LMNADDR1TNFRAB9A | |
| SCHEMBL4210572 | 0.79 | MCL1 (0.61) | MCL1LMNADDR1MAPK1POLB | |
| SCHEMBL12963735 | 0.77 | LMNA (0.61) | MCL1LMNADDR1MAPK1POLB | |
| SCHEMBL24542673 | 0.77 | MCL1 (0.71) | MCL1LMNADDR1TNFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |