Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13717683 | 0.83 | MCL1 (0.58) | MCL1LMNATNFRAB9AHDAC6 | |
| SCHEMBL28856070 | 0.82 | MCL1 (0.56) | MCL1LMNATNFRAB9APOLB | |
| SCHEMBL31241154 | 0.82 | MCL1 (0.56) | MCL1LMNATNFRAB9APOLB | |
| SCHEMBL29843510 | 0.82 | MCL1 (0.56) | MCL1LMNATNFRAB9APOLB | |
| SCHEMBL22447646 | 0.82 | TNF (0.67) | MCL1LMNATNFHDAC6POLB | |
| SCHEMBL12963735 | 0.81 | LMNA (0.61) | MCL1LMNATNFRAB9APOLB | |
| SCHEMBL22447771 | 0.80 | MCL1 (0.58) | MCL1LMNATNFRAB9AHDAC6 | |
| SCHEMBL22447403 | 0.80 | MCL1 (0.58) | MCL1LMNATNFRAB9AMAPK1 | |
| SCHEMBL22447483 | 0.79 | MCL1 (0.54) | MCL1LMNATNFRAB9APIK3CA | |
| SCHEMBL22447583 | 0.79 | MCL1 (0.57) | MCL1LMNATNFRAB9AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712143-A1 | QUINAZOLINONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |