SCHEMBL22448

SCHEMBL22448

C=CC(=O)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12059836 0.73
SCHEMBL1924525 0.72 LMNA (0.44)
SCHEMBL9747332 0.69 LMNA (0.41)
SCHEMBL27603680 0.69 LMNA (0.41)
SCHEMBL27390160 0.69
SCHEMBL8620304 0.69
Acrylic Acid SCHEMBL29018599 0.69
SCHEMBL177716 0.67
SCHEMBL28671774 0.67
SCHEMBL220078 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599644-B Nicotinamide compound and herbicide composition containing the same 韩国化学研究院 2024-08-02 CN disclosed
WO-2023109878-A1 TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF 武汉人福创新药物研发中心有限公司 2023-06-22 WO disclosed
CN-114599644-A Nicotinamide compound and herbicide composition containing the same 韩国化学研究院 2022-06-07 CN disclosed
EP-3873893-A1 2-AMINO-N-HETEROARYL-NICOTINAMIDES AS NAV1.8 INHIBITORS Merck Sharp & Dohme Corp. (US) 2021-09-08 EP disclosed
WO-2020025499-A1 NEW COMPONENTS FOR ELECTROLYTE COMPOSITIONS SOLVAY SA (BE) 2020-02-06 WO disclosed
WO-2012025548-A1 PROCESS FOR THE PREPARATION OF ALKENONES SOLVAY SA (BE) 2012-03-01 WO disclosed
EP-2352723-A2 HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES Bayer CropScience AG (DE) 2011-08-10 EP disclosed
WO-2010051926-A2 NEW HALOGEN-SUBSTITUTED BONDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-05-14 WO disclosed
EP-2164831-A1 METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES Basf Se (DE) 2010-03-24 EP disclosed
WO-2008145740-A1 METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES BASF SE (DE) 2008-12-04 WO disclosed