Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 14/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25199509 | 0.76 | TLR8 (0.67) | TLR8TLR7KCNH2 | |
| SCHEMBL16441112 | 0.75 | TLR8 (0.52) | TLR8TLR7 | |
| SCHEMBL18109645 | 0.75 | TLR8 (0.82) | TLR8TLR7KCNH2 | |
| SCHEMBL18109647 | 0.75 | TLR8 (0.82) | TLR8TLR7KCNH2 | |
| SCHEMBL25194886 | 0.74 | TLR8 (0.72) | TLR8TLR7KCNH2 | |
| SCHEMBL25194884 | 0.74 | TLR8 (0.72) | TLR8TLR7KCNH2 | |
| SCHEMBL16441145 | 0.74 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL16441143 | 0.74 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL17830003 | 0.74 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL25191521 | 0.73 | TLR8 (0.70) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3404031-B1 | THIENO[3,2-D]PYRIMIDINES DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-09-23 | — | — | EP | disclosed |