Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | PRKCI | P41743 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16441144 | 0.85 | TLR8 (0.56) | TLR8TLR7KCNH2 | |
| SCHEMBL17829983 | 0.81 | PRKCI (0.51) | TLR8TLR7PRKCI | |
| SCHEMBL17829996 | 0.77 | TLR8 (0.52) | TLR8TLR7KCNH2 | |
| SCHEMBL17830002 | 0.73 | TLR8 (0.42) | TLR8TLR7PRKCIKCNH2 | |
| SCHEMBL22448319 | 0.70 | TLR8 (0.42) | TLR8TLR7PRKCIKCNH2 | |
| SCHEMBL17830003 | 0.70 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL16441143 | 0.70 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL16441145 | 0.70 | TLR8 (0.60) | TLR8TLR7KCNH2 | |
| SCHEMBL17829984 | 0.68 | TLR8 (0.56) | TLR8TLR7PRKCIKCNH2 | |
| SCHEMBL8377084 | 0.68 | TLR8 (0.38) | TLR8TLR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3404031-B1 | THIENO[3,2-D]PYRIMIDINES DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-09-23 | — | — | EP | disclosed |