Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTH | P32929 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922115 | 0.84 | GAA (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15548998 | 0.84 | CTH (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15549000 | 0.84 | CTH (0.56) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15558824 | 0.84 | CTH (0.54) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15558826 | 0.84 | CTH (0.54) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15617043 | 0.84 | CTH (0.59) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15549859 | 0.80 | MAPT (0.62) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15549856 | 0.80 | MAPT (0.62) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL12416588 | 0.80 | MAPT (0.51) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL15558463 | 0.79 | MAPT (0.55) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2877457-B1 | CYSTATHIONINE-GAMMA-LYASE (CSE) INHIBITORS | SOVA PHARMACEUTICALS INC (US) | 2020-09-23 | — | — | EP | disclosed |