Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 7/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.45 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | CPA1 | P15085 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.40 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.40 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22449123 | 0.89 | ITGB1 (0.48) | MMEACE2ACECPA1ITGB1 | |
| SCHEMBL22449284 | 0.89 | RXRA (0.47) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL15037189 | 0.88 | MME (0.49) | MMEACE2ACECPA1KDM4E | |
| SCHEMBL22449277 | 0.88 | MME (0.49) | MMEACE2ACECPA1KDM4E | |
| SCHEMBL15037300 | 0.86 | MME (0.53) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL22448948 | 0.86 | MME (0.53) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL22449043 | 0.86 | MME (0.53) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL15037188 | 0.86 | MME (0.53) | ALDH1A1MAPTMMEACE2ACE | |
| SCHEMBL15037208 | 0.85 | PTPN1 (0.44) | MMEACE2ACEITGB1ITGA4 | |
| SCHEMBL22448951 | 0.85 | PTPN1 (0.46) | ALDH1A1MAPTMMEACE2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |