Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295278 | 0.88 | ROCK2 (0.49) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL16295279 | 0.88 | ROCK2 (0.49) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL15037039 | 0.86 | MAPT (0.46) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL16342898 | 0.86 | MAPT (0.46) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL22384184 | 0.85 | ROCK2 (0.45) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL15037142 | 0.85 | ROCK2 (0.45) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL22384169 | 0.85 | MAPT (0.45) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL28294750 | 0.85 | MAPT (0.50) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL28294749 | 0.85 | MAPT (0.50) | ROCK2MAPTTDP1POLBNPSR1 | |
| SCHEMBL22384255 | 0.84 | MAPT (0.42) | ROCK2MAPTTDP1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |