Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037055 | 1.00 | L3MBTL1 (0.47) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL22449277 | 0.96 | MME (0.49) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL15037189 | 0.96 | MME (0.49) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL22448948 | 0.94 | MME (0.53) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL22449043 | 0.94 | MME (0.53) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL15037300 | 0.94 | MME (0.53) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL15037188 | 0.94 | MME (0.53) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL15037128 | 0.92 | L3MBTL1 (0.48) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL15037073 | 0.92 | L3MBTL1 (0.48) | L3MBTL1MMEACEACE2PTPN1 | |
| SCHEMBL22449248 | 0.92 | PTPN1 (0.46) | L3MBTL1MMEACEACE2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |